Next generation toxicology and drug development instruments
ABOUT THE LOCSENSE ARTEMIS IMPEDANCE/TEER DETECTOR
The Locsense Artemis is an automated, real-time impedance/TEER detector, providing an objective standard for the barrier integrity. Monitor the barrier integrity, while the cell culture is located inside an incubator. The Artemis can be coupled to transwell plates with inserts and microfluidic chips.The Artemis software is intuitive, suitable for first-time users and provides in-depth analysis of impedance measurements.
CUTTING-EDGE 2D AND 3D CELL CULTURE SENSING
Automated endothelial and epithelial barrier assessment of cell cultures in conventional transwell plates with inserts
CE and UL certified
CULTURE WARE
Complement with the pre-loaded 24 wells plates with non-rotating inserts
ARTEMIS 2D AND 3D CELL CULTURE SENSING
FACTSHEETS AND APPLICATION NOTES
ESSENTIALS ABOUT IMPEDANCE SPECTROSCOPY AND TEER
Preprint
Authors: N.J.M. van den Brink, F. Pardow, L.D. Meesters, I. van Vlijmen-Willems, D. Rodijk-Olthuis, H. Niehues, P.A.M. Jansen, S. H. Roelofs, M.G. Brewer, E.H. van den Bogaard and J.P.H. Smits
Preprint
Authors: Jos P.H. Smits, Jieqiong Qu, Felicitas Pardow, Noa J.M. van den Brink, Diana Rodijk-Olthuis, Ivonne M.J.J. van Vlijmen-Willems, Simon J. van Heeringen, Patrick L.J.M. Zeeuwen, Joost Schalkwijk, Huiqing Zhou, Ellen H. van den Bogaard
Article
Authors: Thanh Huyen Phan, Huaikai Shi Christopher E. Denes, Alexander J. Cole, Yiwei Wang, Yuen Yee Cheng, Daniel Hesselson, Susan H. Roelofs, Graham Gregory Neely, Jun‑Hyeog Jang and Wojciech Chrzanowski
Article
Authors: Jos P.H. Smits, Noa J.M. van den Brink, Luca D. Meesters, Hadia Hamdaoui, Hanna Niehues, Patrick A.M. Jansen, Ivonne M.J.J. van Vlijmen-Willems, Diana Rodijk-Olthuis, Ce´line Evrard, Yves Poumay, Michel van Geel, Wiljan J.A.J. Hendriks, Joost Schalkwijk, Patrick L.J.M. Zeeuwenand Ellen H. van den Bogaard
Poster
Authors: T.H. Phan, H. Shi, C.E. Denes, A.J. Cole, Y. Wang, E. Geervliet, Y.Y. Cheng, D. Hesselson, S.H. Roelofs, G.G. Neely, J.Jang and W.Chrzanowski
Poster
Poster
Authors: Robin Pampiermole, Sandro Meucci, Ruud Das, Juda-El Sam, Tim Segers, Loes Segerink, Kerensa Broersen, Andries van der Meer
Poster
Authors: Edwin van Oosten, Devin Veerman, Stijn Berendsen, Rob Collin, Dirk Lefeber, Loes Segerink, Seba Almedawar, Jürgen Prestle, Parth Patel, Susan Roelofs, Stefan G. Kauschke, Andries van der Meer, Alejandro Garanto
LOCSENSE, TRUSTED PARTNER IN CELL BIOLOGY
WHAT CLIENTS SAY ABOUT US
The Artemis has become an essential piece of technology in a majority of the experimental and quality control workflows in our laboratory.
This system has enabled us to establish reliable, rapid and cost-effective methodologies to assess bioelectrical parameters of cells and tissues. This advancement has sped up our development of sophisticated human-like organ and tissue models. The Artemis is now a key tool for testing the quality of these models and assessing the safety of nanoparticles (such as air pollutants), as well as the safety and efficacy of new therapeutics (like extracellular vesicles) for repairing various organs.
Additionally, using the Artemis has significantly reduced the number of tests needed to evaluate the models and decreased the use of plasticware in the lab, contributing to the sustainability of our research. Lastly, the Locsense team has provided exceptional support with experimental setup and data analysis.
Prof. Wojciech Chrzanowski, The University of Sydney | Faculty of Medicine and HealthWe have been working with the Artemis ST in combination with 24 wells plates during a rental period and were impressed by its performance.
Recently, we purchases one, allowing us to continue utilizing it in our experiments. The Artemis has been instrumental in generating reliable data on barrier integrity across various in vitro models, significantly enhancing the robustness of our experimental setups.
Moreover, the Artemis has enabled us to investigate time-dependent barrier effects, which we were previously unable to study in-depth. Its user-friendly interface and space-efficient design make it an excellent addition to our laboratory.
The Locsense team has consistently demonstrated professionalism and dedication, always putting in effort to meet our needs. Their support in experimental setup and data analysis has been very valuable. We look forward to continuing our collaboration with Locsense and incorporating the Artemis further in our research.
Dr. Marit Zuurveld, Utrecht University
THEY TRUST US
ABOUT LOCSENSE
Locsense was founded in 2016 in Enschede and is revolutionizing how we monitor, measure, and test cells right from the lab bench, offering a cruelty-free alternative to animal testing. Our flagship device, the Locsense Artemis, is a non-invasive sensor that monitors cell health, enabling groundbreaking discoveries in fields like cosmetics, pharmaceuticals and the food industry.
Locsense is at the forefront of lab technology with devices that non-invasively monitor and test cells outside the body. In our bodies, cells often form protective barriers. Think of these barriers as tiny walls that separate different areas. For example, the lining of your gut has cells that create a barrier between your food and the rest of your body, or the skin which forms a protective barrier for influences from outside.
Impedance measurements offer a way to measure how strong these barriers are and whether they are intact. The Artemis offers insight into how healthy cell barriers are. This is crucial for drug testing, studying diseases, and making sure our body’s defenses work properly.
Our products are designed to combine with conventional workflow. At the same time they can be coupled to innovative in-vitro cell culture platforms, such as microfluidic chips, organs-on-chip or smartplates.
VACANCIES
IN THE NEWS TODAY
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NXTGEN HIGHTECH – Biomed 03: Organ-on-Chip
Kick off NXTGEN HIGHTECHThe NXTGEN HIGHTECH biomedical 3 project has officially kicked off with a workshop on Competences, Needs and Gaps in Fabrication for Biomedical [...]
SOT from 10th-14th of March 2024 in Salt lake city
Locsense exhibitor at the SOT ToxExpo in Salt Lake CityLocsense will exhibit at the 70th SOT Annual meeting and ToxExpo in Salt Lake City, Utah [...]
Eurostars funding Epithelial Sensing
Innovative skin sensing for drug and cosmetic compounds testingLocsense, StratiCELL and the Radboudumc are proud to announce Eurostars funding supporting the development of a breakthrough [...]
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LOCSENSE B.V.
Visiting address:
Institutenweg 25
7521 PH Enschede
Phone: +31(0)6-10499335
Email: info@locsense.nl
Web: www.locsense.nl