Impedance spectroscopy and TEER detection

ABOUT THE LOCSENSE ARTEMIS IMPEDANCE/TEER DETECTOR

The Locsense Artemis is an automated, real-time impedance/TEER detector, providing an objective standard for the barrier integrity. Impedance/TEER measurements were never this easy. Monitor the barrier integrity, while the cell culture is located inside an incubator. The Artemis can be coupled to transwell plates with inserts and microfluidic chips.The Artemis software is intuitive, suitable for first-time users and in-depth analysis of impedance measurements.

Automated TEER / impedance spectroscopy measurements

Monitor the barrier function while cells are situated inside the incubator or on the laboratory bench

User-friendly and workflow compatible

The software is plug and play and the system is easy to operate for first time users

Time-saving

Save time by automating TEER / impedance spectroscopy measurements for several hours or days at the desired time intervals

Non-destructive, semi-continuous

The Artemis operates while cells are located inside the incubator, hood or on the desktop. Measurements are non-destructive and can be performed for days in a row and intervals of your choice.

Compatible with conventional transwell plates

Smart-lids are available for 12 and 24 wells transwell plates, including Nunc, Corning, VWR, Greiner.

Reduced risk of cross contamination

Each well is equipped with a set of electrodes, thereby reducing the risk of cross contamination. All parts in contact with cells are autoclavable

CUTTING-EDGE 2D AND 3D CELL CULTURE SENSING

Automated endothelial and epithelial barrier assessment of cell cultures in conventional transwell plates with inserts

Artemis

12 wells

10 Hz – 100 kHz

separate smartlid

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Artemis ST Single Transwell

24 wells

10 Hz – 100 kHz

integrated design

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Artemis MT Multi Transwell

4 x 24 wells

10 Hz – 100 kHz

integrated design

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CULTURE WARE

Complement with the pre-loaded 24 wells plates with non-rotating inserts

non rotating inserts

transparent PET membranes

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non rotating inserts

translucent PET membranes

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ARTEMIS 2D AND 3D CELL CULTURE SENSING

locsense lineup_Tekengebied_crop_resized

Calibration Tool

Mimic Cells in Culture

Regular time-intervals

Intuitive

10 Hz – 1 MHz

12 Channels

Incubator compatible

Easy to Clean

FACTSHEETS AND APPLICATION NOTES

ESSENTIALS ABOUT IMPEDANCE SPECTROSCOPY AND TEER

preprint The aryl hydrocarbon receptor regulates epidermal differentiation through transient activation of TFAP2A

research article Investigations into the FLG Null Phenotype: Showcasing the Methodology for CRISPR/Cas9 editing of human keratinocytes

research article Advanced pathophysiology mimicking lung models for accelerated drug discovery

Poster electrical impedance spectroscopy analysis to evaluate organotypic epidermis formation and barrier function in vitro

Poster Developing a scalable hiPSC-derived blood-brain barrier model

Poster RETINA ON CHIP; Modeling and treaTng eye diseases in a dish

QUICK GUIDE TO IMPEDANCE DETECTION WITH THE ARTEMIS

Technical note Impedance spectroscopy

ARTEMIS BROCHURE

Artemis SPECIFICATIONS

LOCSENSE, TRUSTED PARTNER IN CELL BIOLOGY

The Artemis is unique in it’s smart workflow, sensitivity and flexibility. Locsense provides a total solution for quantitative cellular barrier measurements. Demonstrated e.g. for 3D skin constructs, gut tissue and cardiomyocytes.

ABOUT LOCSENSE

Locsense was founded in 2016 in Enschede. We contribute to reduction and replacements of animal testing for drug development and cosmetics, by providing measurement equipment for in-vitro tests. Our products are designed to combine with conventional workflow. At the same time they can be coupled to innovative culture platforms, such as microfluidic chips, organs-on-chip or smartplates.

Susan RoelofsCEO and founder

Navin ReddySoftware engineer

Parth PatelElectrical engineer

Erwin de VriesSoftware engineer

Iris KormelinkBiomedical engineer

Wei-Ting SunData scientist

Get Hands On With Locsense Technology

Get a Quote

VACANCIES

Electrical engineer

admin2023-10-02T08:28:46+00:00oktober 2nd, 2023|Categories: Vacancies|

Werkstudent marketing and sales

admin2023-10-02T13:33:30+00:00oktober 1st, 2023|Categories: Vacancies|

Embedded software engineer

admin2023-06-12T08:27:04+00:00juni 11th, 2023|Categories: Vacancies|

IN THE NEWS TODAY

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Eurostars funding Epithelial Sensing

Eurostars funding Epithelial Sensing

admin2023-09-20T11:29:50+00:00september 19th, 2023|

Locsense, StratiCELL and the Radboudumc are proud to announce Eurostars funding supporting the development of a breakthrough Epithelial Sensing solution that accurately measures the [...]

E2BRN 2023 conference in Edinburgh

E2BRN 2023 conference in Edinburgh

admin2023-08-15T18:34:44+00:00augustus 15th, 2023|

Felicitas Pardow and Jos P.H. Smits from the Radboudumc will present their findings on how impedance spectroscopy provides insight in epidermis formation and skin [...]